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Dr. Manjushree Aithal
Dr. Manjushree Aithal, PhD - AI and Systems Researcher

Manjushree Aithal, PhD

Postdoctoral Fellow at CU Anschutz • Ex-Lenovo Research

Hello There!

Full Name:
Manjushree Aithal, PhD
Pronunciation:
/mahn-joo-shree eye-thahl/
Affiliation:
The Mitchell Lab, Dept of Biomedical Informatics, University of Colorado Anschutz
Research Focus:
HCI ✦ Clinical NLP ✦ Privacy Preserving AI ✦ Agentic Framework ✦ On-device optimization ✦ Camera AI ✦ Computer Vision ✦ Adversarial Attacks & Defenses

I am a computational researcher with proven experience across machine learning, clinical language models, agentic systems, and on-device optimization. At the University of Colorado Anschutz (The Mitchell Lab), my work centers on human-centered clinical AI, designing privacy-preserving architectures that bring language models directly to edge devices under HIPAA constraints, and engineering autonomous multi-agent frameworks that automate requirement-elicitation and patient simulations.

Prior to my postdoctoral fellowship, I served as a Staff Researcher and AI Camera Researcher at Lenovo Research, delivering mission-critical Gen-AI platform features (gaze and blink correction), ultra-lightweight super-resolution modules (8ms latency), and novel GAN training pipelines with automated CI/CD benchmarking.

I completed my PhD in Electrical and Computer Engineering at Binghamton University under Dr. Xiaohua Li, investigating adversarial defense mechanisms and query optimization in deep learning. I thrive at the intersection of rigorous scientific research and production deployment.

Professional Memberships
IEEE
Member
ACM SIGCHI
HCI Member
AMIA
Biomedical Info
IMIA-SEP
Global Member

Recent News

2025 - 2026
Sep 2026 Recognition
Officially recognized and verified member of the Influential Women community.
Aug 2026 Conference
Presented poster on LadderTeam at the ACM AI Leadership Summit (Atlanta, GA) with ACM Travel Grant support.
Aug 2026 Mentorship
Mentored high school students on Clinical AI research projects (PLACID and cancer severity detection) in the CU Anschutz Summer Science Discover Program; received official Letter of Acknowledgement.
May 2026 Fellowship
Awarded the CU Innovations Fellowship (duration: FY26/27, 2026–2027) to build MiniGali, a local, privacy-preserving retrieval-augmented agent for institutional program knowledge.
Mar 2026 Paper & Poster
Published and presented poster for benchmark dataset paper "LENVIZ: A High-Resolution Low-Exposure Night Vision Benchmark Dataset" at IEEE/CVF WACV 2026 (Tucson, AZ).
March 2025 Award
Received Lenovo's company-wide SVP Individual Excellence Award for enterprise Gen-AI platform features and automation.

Key Research Projects

Flagship architectures across clinical AI, agentic systems, and computer vision

SOB ? Clinical EHR Stage 1: Detect 98.8% Acc (2B) Instruction SLM Contextual Bio Stage 2: Expand 0.65 → 0.81 Acc Biomedical LLM ON-DEVICE Zero Egress HIPAA Safe
Clinical AI • CU Anschutz 2025 – Present

PLACID: Privacy-Preserving Clinical Acronym Disambiguation

Architected a two-stage cascade routing general-purpose instruction models for acronym detection to domain-specific biomedical models for context expansion. Benchmarked on local small models (2B–10B) achieving ~0.988 detection accuracy and raising expansion accuracy to ~0.81 with zero external data egress.

Preprint: arXiv:2603.23678
👤 Clinical User Domain Expert Simulated Turns Interactive Loop Interviewer --> Probe Reply 💬 Interviewer Agent Alpha ACV • 5-Whys • JTBD Probing Engine Turns Score ⚖️ Judge Agent Silent Evaluator Convergence: 99.1% Drift: 0% (0/216) Action Match: 81.0% Zero-Interruption Evaluation
Multi-Agent Systems • CU Anschutz 2025 – Present

LadderTeam: Dual-Agent Elicitation Framework

Architected a dual-agent (Interviewer & Judge) framework automating laddering interviews (ACV, 5-Whys, JTBD). Built a reproducible 5-step per-turn loop with drift detection and non-interrupting evaluation judging. Achieved 99.1% chain convergence and zero drift across 216 controlled simulation runs.

Preprint: arXiv:2608.17029
Sensor Feed Raw Frames Edge Ingestion Gen-AI Generator Gaze & Blink Sync Attention Alignment Novel GAN Pipeline Facial Re-alignment Ultra-Lightweight SR 8ms Latency +71MB GPU Footprint Qualcomm / MediaTek Mobile Edge Inference 60 FPS Live Output
Computer Vision • Lenovo Research 2022 – 2025

Enterprise Gen-AI Camera & Model Optimization

Engineered generator architecture for enterprise Gen-AI (blink and gaze correction) with lightweight 8ms Super Resolution module (+71MB GPU). Designed scalable novel GAN CI/CD infrastructure improving training efficiency by 40% and cutting manual QA by 85%. Led A/B testing dashboards that cut testing cycle from 6 to 2 hours.

Lenovo SVP Individual Excellence Award Recognition
x + δ Adversarial Input Black-Box Attack Threat Vector Defense Algorithm Manifold Projection Pretrained VAE • DCGAN Query Optimization Noise Purification Projected to Safe Manifold 100% Attack Mitigation Black-Box Evaluation Robust Decision Boundary
AI Robustness & Security • PhD Thesis Binghamton University (2019–2022)

Mitigating Adversarial Attacks in Deep Learning Systems

Investigated adversarial vulnerability and developed defense algorithms against state-of-the-art black-box adversarial attacks, achieving 100% attack mitigation rate for critical applications. Implemented evaluation pipelines using Cleverhans and ART in PyTorch/TensorFlow, and researched pretrained VAE and DCGAN architectures for query optimization.

IEEE Access • ICPR 2022 View Papers →

Experience & Background

Chronological summary of research appointments, industry leadership, and academic instruction

Postdoctoral Fellow: Clinical AI Framework Development

Current
Dec 2025 – Present
The Mitchell Lab, Department of Biomedical Informatics, University of Colorado Anschutz

Developing privacy-preserving clinical language model architectures and autonomous multi-agent requirement elicitation frameworks for healthcare systems under strict HIPAA and data-privacy constraints.

Staff Researcher & AI Camera Researcher

Nov 2022 – Oct 2025
Lenovo Research, IL

Led enterprise Gen-AI camera feature development (blink and gaze correction), lightweight super-resolution modules (8ms latency), novel GAN training CI/CD pipelines, and PEFT/LoRA mobile deployment optimization across Qualcomm and MediaTek architectures. Recipient of Lenovo SVP Individual Excellence Award.

Graduate Research Fellow: AI Robustness & Security

Aug 2019 – Oct 2022
Binghamton University, NY

Researched adversarial vulnerabilities in deep neural networks and developed defense algorithms achieving 100% attack mitigation against black-box adversarial attacks. Implemented evaluation suites with Cleverhans and ART toolboxes in PyTorch and TensorFlow.

Teaching Assistant: Engineering Design Division (EDD)

2019 – 2022
Binghamton University, NY

Taught undergraduate courses in signal processing and mentored senior capstone engineering design projects over 3 years. Developed instructional curricula covering coding, CAD, and circuit design; awarded Binghamton Teaching Excellence Award.

Hardware Engineering Research Intern (Co-op)

Jan 2018 – Jun 2018
Universal Instruments Co, NY

Developed high-speed wafer feeder systems using Xilinx platforms with precision spindle switching mechanisms. Programmed embedded code for FIFO and power control systems, and implemented digital filters for high-speed noise cancellation.

Education

Oct 2022
Ph.D. in Electrical & Computer Eng.
Binghamton University, NY
GPA: 3.9 / 4.0
Advisor: Dr. Xiaohua Li
Sep 2015
M.E. in Electronics & Telecom
Pune University, India
Thesis: Speech Enhancement Using PCA for Emotion Recognition
May 2012
B.E. in Electronics & Telecom
Shivaji University, India
Magna Cum Laude

Publications & Presentations

All peer-reviewed journal papers, conference proceedings, preprints, and symposium posters

Peer-Reviewed Publications & Preprints

LadderTeam: Dual-Agent Laddering Elicitation Framework.
Aithal, M., Kotz, A., & Mitchell, J. (2026). arXiv preprint arXiv:2608.17029.
PLACID: Privacy-preserving Large language models for Acronym Clinical Inference and Disambiguation.
Aithal, M., Kotz, A., & Mitchell, J. (2026). arXiv preprint arXiv:2603.23678.
LENVIZ: A High-Resolution Low-Exposure Night Vision Benchmark Dataset.
Aithal, M., Vidal Mata, R.G., Kartha, M., Chen, G., Adhikarla, E., Kirsten, L.N., Fu, Z., Madhusudhana, N.A., Nasti, J.V. (2026). IEEE/CVF Winter Conference on Applications of Computer Vision (WACV), 2531–2540.
Unified-EGformer: Exposure Guided Lightweight Transformer for Mixed-Exposure Image Enhancement.
Adhikarla, E., Zhang, K., VidalMata, R.G., Aithal, M., Madhusudhana, N.A., Nicholson, J., Davison, B.D. (2024). International Conference on Pattern Recognition (ICPR), Springer Nature, pp. 260–275.
Mitigating Black-Box Adversarial Attacks via Output Noise Perturbation.
Aithal, M., & Li, X. (2022). IEEE Access Journal, vol. 10, pp. 12395–12411.
IEEE Access
Boundary Defence Against Black-box Adversarial Attacks.
Aithal, M., & Li, X. (2022). 26th International Conference on Pattern Recognition (ICPR), pp. 2349–2356.
Emotion Detection from Distorted Speech Signal using PCA-Based Technique.
Aithal, M.B., & Sahare, S.L. (2015). International Journal of Innovative Research in Advanced Engineering, 2(9).
IJIRAE 2015
Speech Enhancement Using PCA for Speech and Emotion Recognition.
Gaikwad, P.R., Aithal, M.B., & Sahare, S.L. (2015). Global Journal of Engineering, Design and Technology, 4(3), 6–12.
GJEDT 2015

Posters & Presentations

LadderTeam: Dual-Agent Laddering Elicitation Framework.
Aithal, M.B., Kotz, A., Mitchell, J. (2026). ACM AI Leadership Summit, Atlanta, GA • Poster Presentation
ACM Summit 2026
PLACID: Privacy-preserving Large Language Models for Acronym Clinical Inference and Disambiguation.
Aithal, M.B., Kotz, A., Mitchell, J. (2026). Women in Machine Learning (WiML) Workshop @ NeurIPS • AMIA Symposium
WiML @ NeurIPS AMIA (Upcoming)
LENVIZ: A High-Resolution Low-Exposure Night Vision Benchmark Dataset.
Aithal, M., Vidal Mata, R.G., Kartha, M., et al. (March 2026). IEEE/CVF Winter Conference on Applications of Computer Vision (WACV), Tucson, AZ
WACV 2026
Boundary Defence Against Black-box Adversarial Attacks.
Aithal, M., & Li, X. (2022). 26th International Conference on Pattern Recognition (ICPR), Montreal, QC, Canada • Paper Presentation
ICPR 2022
✦ Let’s Connect & Collaborate

Curious to Learn More or Collaborate?

Always open to exploring new ideas, research collaborations, speaking opportunities, and scientific discussions.